If you’ve been wondering what the Elixir of Life does in Anime Astral Simulator, it’s easily one of the best permanent upgrades added in Mini Update 7.5. Unlike temporary buffs that disappear after a run, this artifact keeps getting stronger the more you play, making it an investment that pays off throughout your entire progression.
The catch? You won’t unlock it in just a few minutes. You’ll need to collect four different fragments from various game modes before you can craft it, and fully upgrading it requires over 215,000 enemy kills.
It sounds like a lot, but don’t let that number scare you. Since every kill contributes to its progress, you’ll naturally level it up while farming other content. In this guide, I’ll explain where every fragment drops, how to craft the artifact, and the fastest way to level it to the maximum 6x damage bonus.
Anime Astral Simulator Elixir of Life Guide – All Fragments
The Elixir of Life is a permanent artifact introduced in Mini Update 7.5.
Once crafted and equipped, it increases your overall damage, and the bonus grows as the artifact gains levels. Unlike equipment that becomes outdated after reaching a new world, the Elixir of Life remains useful throughout your entire journey.
At Level 1, it immediately grants:
- 1.5x Damage
From there, every level increases your damage multiplier until it reaches the maximum bonus at Level 10.
Requirements Before You Can Craft It
Before you start farming fragments, you’ll first need access to Solo City, which is World 5.
Solo City is important because that’s where you’ll find the Elixir of Life Crafting Station. Even if you collect every fragment beforehand, you won’t be able to craft the artifact until you’ve unlocked this world.
How to Get Elixir of Life Fragment I
The first fragment is one of the easiest to obtain.
Drop Source:
- Any Gate in Solo City (World 5)
Simply keep clearing Gates in Solo City until the fragment drops.
If you’re already farming Gates for other rewards, you’ll likely obtain this fragment naturally without changing your routine.
How to Get Elixir of Life Fragment II
The second fragment comes from Defense Mode.
You can farm it in either of these worlds:
- Titan Wall (World 4)
- Summer Art Online (World 8)
Choose whichever location matches your current progression. If you’ve already unlocked World 8 and can clear it comfortably, that may be the better farming option. Otherwise, Titan Wall is perfectly fine.
How to Get Elixir of Life Fragment III
Fragment III drops from more challenging activities.
You can obtain it from:
- Trials in the Lobby Arena
- Dungeons in Fire City (World 9)
This fragment usually takes a little longer because it’s tied to harder content, but the good news is you’ll also earn plenty of useful materials, currency, and progression rewards while farming it.
How to Get Elixir of Life Fragment IV
The final fragment comes from World Bosses.
Eligible bosses include:
- Ninja Village
- Namek City
- Wayno Island
- Titan Wall
- Solo City
- Slayer Village
- Clover Island
- Summer Art Online
- Fire City
- Waiko World
- Cursed School
Since multiple bosses can drop the fragment, don’t worry about chasing a specific one.
Instead, repeatedly farm whichever boss your team defeats the fastest. Faster clears usually mean more attempts and better chances of getting the fragment.
How to Craft the Elixir of Life
After collecting all four fragments:
- Open the Teleport menu.
- Travel to Solo City (World 5).
- Locate the Elixir of Life Crafting Station.
- Combine all four fragments.
- Craft the completed artifact.
- Equip it from your inventory.
Once equipped, every enemy you defeat begins contributing toward its next level.
How to Level Up the Elixir of Life
One of the best things about this artifact is that it levels up through normal gameplay.
Enemy kills count from almost every activity, including:
- Story Worlds
- Gates
- Trials
- Dungeons
- Defense Mode
- World Boss farming
Because of this, you don’t need to grind a special game mode just for the artifact.
Simply keep playing whatever content you’re already farming, and your Elixir of Life will continue gaining experience in the background.
Elixir of Life Damage Multiplier by Level
Here’s how the damage bonus increases as you level the artifact.
| Level | Damage Bonus |
|---|---|
| Level 1 | 1.5x Damage |
| Level 2 | 2.0x Damage |
| Level 3 | 2.5x Damage |
| Level 4 | 3.0x Damage |
| Level 5 | 3.5x Damage |
| Level 6 | 4.0x Damage |
| Level 7 | 4.5x Damage |
| Level 8 | 5.0x Damage |
| Level 9 | 5.5x Damage |
| Level 10 | 6.0x Damage |
Reaching Level 10 transforms the Elixir of Life into one of the strongest permanent damage boosts currently available in the game.
How Many Kills Are Needed?
To fully max out the Elixir of Life, you’ll need a total of:
215,282 enemy kills
There’s no way around it—this is a long-term grind.
Fortunately, every kill counts regardless of where it comes from, so you don’t have to interrupt your normal progression just to level the artifact.
Fastest Way to Reach Level 10
Since kills are what matter, you should focus on activities that spawn large numbers of enemies instead of only fighting bosses.
Some of the best farming options include:
- Gates with lots of enemy waves
- Dungeons
- Trials
- Defense Mode
- Story stages with high enemy counts
These activities allow you to:
- Gain thousands of kills
- Farm additional fragments
- Earn currency
- Collect upgrade materials
- Progress other systems at the same time
Bosses are useful for Fragment IV, but once you’ve obtained it, enemy-heavy stages are generally much better for leveling the artifact quickly.
Is the Elixir of Life Worth Farming?
Absolutely.
Even before it’s fully upgraded, the artifact provides a noticeable increase in damage. At just Level 1, the 1.5x multiplier already helps speed up farming, making future progression easier.
As you continue playing, the bonus steadily increases until it reaches an incredible 6x damage multiplier at Level 10. Since every enemy defeated contributes toward its growth, you’re constantly making progress without having to dedicate your entire play session to leveling the artifact.
If you’re planning to spend a lot of time in Anime Astral Simulator, the Elixir of Life is one of the smartest long-term investments you can make.
The Elixir of Life isn’t designed to be completed overnight, and that’s what makes it such a rewarding artifact. Collecting the four fragments takes you through several different game modes, while leveling it encourages you to keep progressing naturally instead of grinding one repetitive activity forever.
My advice is simple: craft it as soon as you unlock Solo City, equip it immediately, and then forget about the level grind. Continue farming Gates, Trials, Dungeons, Defense Modes, and World Bosses as you normally would. Before you know it, those kills will add up, your damage multiplier will keep climbing, and you’ll eventually unlock the full 6x damage bonus without feeling like you were grinding it separately.